General Information

    • DRAMP ID

    • DRAMP01057

    • Peptide Name

    • 30 kDa antifungal protein (Plants)

    • Source

    • Engelmannia peristenia (Engelmann's daisy) (Engelmannia pinnatifida)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • XXTKFDFFTLALQXPAXF

    • Sequence Length

    • 18

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Gaeumannomyces graminis, Phytophthora infestans, Phytophthora megasperma, Sclerotinia sclerotiorum.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01057 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01057.

Physicochemical Information

    • Formula

    • C82H108N16O16

    • Absent Amino Acids

    • CEGHIMNRSVWY

    • Common Amino Acids

    • FX

    • Mass

    • 2091.24

    • PI

    • 5.84

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 8

    • Net Charge

    • 0

    • Boman Index

    • 0.43

    • Hydrophobicity

    • 0.472

    • Aliphatic Index

    • 54.44

    • Half Life

      • Mammalian:?
      • Yeast:?
      • E.coli:?

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 2

DRAMP01057

DRAMP01057 chydropathy plot

Comments Information

    • Function

    • Has antifungal activity against the plant fungal pathogens. Does not have antifungal activity against the human pathogen C. albicans. Does not have ribonuclease activity.

    • Tissue specificity

    • Leaves.

    • Developmental stage

    • Expressed in young plants, no expression in mature plants.

    • Miscellaneous

    • Resistant to heat and proteolysis.

    • Biophysicochemical properties

    • Temperature dependence (Thermostable).

Literature Information

  • ·Literature 1

    • Title

    • Isolation and characterization of a 30 kDa protein with antifungal activity from leaves of Engelmannia pinnatifida.

    • Reference

    • Biochem J. 1996 Jun 15;316 ( Pt 3):723-727.

    • Author

    • Huynh QK, Borgmeyer JR, Smith CE, Bell LD, Shah DM.