General Information

    • DRAMP ID

    • DRAMP01084

    • Peptide Name

    • Alyteserin-2b (toads, amphibians, animals)

    • Source

    • Alytes obstetricans (European midwife toad)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ILGAILPLVSGLLSNKL

    • Sequence Length

    • 17

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01084 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01084.

Physicochemical Information

    • Formula

    • C81H145N19O21

    • Absent Amino Acids

    • CDEFHMQRTWY

    • Common Amino Acids

    • L

    • Mass

    • 1721.16

    • PI

    • 8.75

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +1

    • Boman Index

    • 28.1

    • Hydrophobicity

    • 1.553

    • Aliphatic Index

    • 206.47

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP01084

Comments Information

    • Function

    • Amtimicrobial peptide. (By similarity)

Literature Information

  • ·Literature 1

    • Title

    • The alyteserins: two families of antimicrobial peptides from the skin secretions of the midwife toad Alytes obstetricans (Alytidae).

    • Reference

    • Peptides. 2009 Jun;30(6):1069-1073.

    • Author

    • Conlon JM, Demandt A, Nielsen PF, Leprince J, Vaudry H, Woodhams DC.