General Information
-
DRAMP ID
- DRAMP01086
-
Peptide Name
- Alyteserin-2c (toads, amphibians, animals)
-
Source
- Alytes obstetricans (European midwife toad)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- ILGAILPLVSGLLSSKL
-
Sequence Length
- 17
-
UniProt Entry
- No entry found
-
Protein Existence
- Predicted
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal, Antiviral
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01086.
Physicochemical Information
-
Formula
- C80H144N18O21
Absent Amino Acids
- CDEFHMNQRTWY
Common Amino Acids
- L
Mass
- 1694.13
PI
- 8.75
Basic Residues
- 1
Acidic Residues
- 0
Hydrophobic Residues
- 10
Net Charge
- +1
-
Boman Index
- 31.34
Hydrophobicity
- 1.712
Aliphatic Index
- 206.47
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 5
DRAMP01086
Comments Information
Function
- Amtimicrobial peptide. (By similarity)
Literature Information
- ·Literature 1
-
Title
- The alyteserins: two families of antimicrobial peptides from the skin secretions of the midwife toad Alytes obstetricans (Alytidae).
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Pubmed ID
- 19463738
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Reference
- Peptides. 2009 Jun;30(6):1069-1073.
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Author
- Conlon JM, Demandt A, Nielsen PF, Leprince J, Vaudry H, Woodhams DC.