General Information
-
DRAMP ID
- DRAMP01092
-
Peptide Name
- Alytesin (toads, amphibians, animals)
-
Source
- Alytes obstetricans (Common midwife toad) (Bufo obstetricans)
-
Family
- Belongs to the bombesin/neuromedin-B/ranatensin family
-
Gene
- Not found
-
Sequence
- QGRLGTQWAVGHLM
-
Sequence Length
- 14
-
UniProt Entry
- P08944
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Unknown
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01092.
Physicochemical Information
-
Formula
- C68H108N22O18S
Absent Amino Acids
- CDEFIKNPSY
Common Amino Acids
- G
Mass
- 1553.8
PI
- 9.76
Basic Residues
- 2
Acidic Residues
- 0
Hydrophobic Residues
- 5
Net Charge
- +2
-
Boman Index
- -10.04
Hydrophobicity
- -0.143
Aliphatic Index
- 83.57
Half Life
-
- Mammalian:0.8 hour
- Yeast:10 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 423.08
Polar Residues
- 4
DRAMP01092
Comments Information
Function
- Amphibian defensive peptide.
Tissue specificity
- Expressed by the skin glands.
Literature Information
- ·Literature 1
-
Title
- Active peptides in the skins of one hundred amphibian species from Australia and Papua New Guinea.
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Pubmed ID
- 6141890
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Reference
- Comp Biochem Physiol C. 1984;77(1):99-108.
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Author
- Erspamer V, Erspamer GF, Mazzanti G, Endean R.