General Information
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DRAMP ID
DRAMP01105
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Peptide Name
Maximin-S4 (chain of Maximins-S type B/C; toads, amphibians, animals)
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Source
Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)
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Family
Belongs to the bombinin family
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Gene
Unknown
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Sequence
RSNKGFNFMVDMIQALSK
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Sequence Length
18
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Evidence code
Protein level
Activity Information
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Biological Activity
Antibacterial, Antimicrobial
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Target Organism
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- [Ref.15649437]Mycoplasma humenis (MIC=46 µM), Ureaplasma urealyticum (MIC=46 µM).
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Hemolytic activity
-
- [Ref:15649437]Non-hemolytic activity
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Binding Target
Unknown
Structure Information
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Structure
Unknown
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Structure Description
Unknown
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PDB ID
Unknown
-
-
Physical Information
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Formula
C91H148N26O26S2
Absent Amino Acids
CEHPTWY
Common Amino Acids
FKMNS
Mass
2389.86
PI
10.79
Basic Residues
3
Acidic Residues
1
Hydrophobic Residues
6
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Boman Index
-33.07
Hydrophobicity
-25.56
Aliphatic Index
65
Half Life
-
- Mammalian:1 hour
- Yeast:2 min
- E.coli:2 min
Extinction Coefficient Cystines
0
Absorbance 280nm
0
Polar Residues
5
DRAMP01105

Comments Information
Function
Maximin-S3 has an activity against mycoplasma but has no activity against common Gram-positive and Gram-negative bacteria nor fungi. Has no hemolytic activity. Tissue specificity
Literature Information
- Literature 1
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Pubmed ID
15649437
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Reference
Biochem Biophys Res Commun. 2005 Feb 18;327(3):945-951.
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Author
Wang T, Zhang J, Shen JH, Jin Y, Lee WH, Zhang Y.
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Title
Maximins S, a novel group of antimicrobial peptides from toad Bombina maxima.