• DRAMP ID

    • DRAMP01105
    • Peptide Name

    • Maximin-S4 (chain of Maximins-S type B/C; toads, amphibians, animals)
    • Source

    • Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)
    • Family

    • Belongs to the bombinin family
    • Gene

    • Unknown
    • Sequence

    • RSNKGFNFMVDMIQALSK
    • Sequence Length

    • 18
    • Evidence code

    • Protein level
    • Biological Activity

    • Antibacterial, Antimicrobial
    • Target Organism

      • [Ref.15649437]Mycoplasma humenis (MIC=46 µM), Ureaplasma urealyticum (MIC=46 µM).
    • Hemolytic activity

      • [Ref:15649437]Non-hemolytic activity
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01105 helical wheel diagram
    • Formula

    • C91H148N26O26S2
    • Absent Amino Acids

    • CEHPTWY
    • Common Amino Acids

    • FKMNS
    • Mass

    • 2389.86
    • PI

    • 10.79
    • Basic Residues

    • 3
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 6
    • Boman Index

    • -33.07
    • Hydrophobicity

    • -25.56
    • Aliphatic Index

    • 65
    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP01105

DRAMP01105 chydropathy plot
    • Function

    • Maximin-S3 has an activity against mycoplasma but has no activity against common Gram-positive and Gram-negative bacteria nor fungi. Has no hemolytic activity. Tissue specificity
  • Literature 1
    • Reference

    • Biochem Biophys Res Commun. 2005 Feb 18;327(3):945-951.
    • Author

    • Wang T, Zhang J, Shen JH, Jin Y, Lee WH, Zhang Y.
    • Title

    • Maximins S, a novel group of antimicrobial peptides from toad Bombina maxima.