General Information
-
DRAMP ID
- DRAMP01114
-
Peptide Name
- Maximin-8 (toads, amphibians, animals)
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Source
- Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)
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Family
- Belongs to the bombinin family
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Gene
- Not found
-
Sequence
- GIGTKILGGLKTAVKGALKELASTYVN
-
Sequence Length
- 27
-
UniProt Entry
- Q58T56
-
Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal
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Target Organism
-
- [Ref.15770703]Yeast: Candida albicans
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Hemolytic Activity
-
- [Ref:15770703]Little hemolytic activity
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01114.
Physicochemical Information
-
Formula
- C122H212N32O36
Absent Amino Acids
- CDFHMPQRW
Common Amino Acids
- G
Mass
- 2703.22
PI
- 9.83
Basic Residues
- 4
Acidic Residues
- 1
Hydrophobic Residues
- 11
Net Charge
- +3
-
Boman Index
- 0.83
Hydrophobicity
- 0.341
Aliphatic Index
- 119.26
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 1490
Absorbance 280nm
- 57.31
Polar Residues
- 11
DRAMP01114
Comments Information
Function
- It has little hemolytic activity.
Literature Information
- ·Literature 1
-
Title
- Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
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Pubmed ID
- 15770703
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Reference
- Eur J Immunol. 2005 Apr;35(4):1220-1229.
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Author
- Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.