• DRAMP ID

    • DRAMP01127
    • Peptide Name

    • Maximin-H5 (toads, amphibians, animals)
    • Source

    • Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)
    • Family

    • Belongs to the bombinin family
    • Gene

    • Not found
    • Sequence

    • ILGPVLGLVSDTLDDVLGIL
    • Sequence Length

    • 20
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01127 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01127.
    • Formula

    • C93H160N20O29
    • Absent Amino Acids

    • ACEFHKMNQRWY
    • Common Amino Acids

    • L
    • Mass

    • 2022.41
    • PI

    • 3.42
    • Basic Residues

    • 0
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 11
    • Net Charge

    • -3
    • Boman Index

    • 22.17
    • Hydrophobicity

    • 1.48
    • Aliphatic Index

    • 199.5
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP01127

DRAMP01127 chydropathy plot
    • Comment

    • A arginine mutant (i.e. 3D to 3R) was found to be HIV inhibitory (Wang G et al. 2010 Antimicrob. Agents Chemother. 54
  • ·Literature 1
    • Title

    • An anionic antimicrobial peptide from toad Bombina maxima.
    • Reference

    • Biochem Biophys Res Commun 2002 Jul 26;295(4):796-799.
    • Author

    • Lai R, Liu H, Hui Lee W, Zhang Y.