General Information

    • DRAMP ID

    • DRAMP01144

    • Peptide Name

    • Uperin-2.6 (toads, amphibians, animals)

    • Source

    • Uperoleia mjobergii (Australian toadlet)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GILDIAKKLVGGIRNVLGI

    • Sequence Length

    • 19

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01144 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01144.

Physicochemical Information

    • Formula

    • C89H161N25O23

    • Absent Amino Acids

    • CEFHMPQSTWY

    • Common Amino Acids

    • GI

    • Mass

    • 1949.41

    • PI

    • 9.99

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +2

    • Boman Index

    • 6.71

    • Hydrophobicity

    • 0.984

    • Aliphatic Index

    • 179.47

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP01144

DRAMP01144 chydropathy plot

Comments Information

    • Function

    • Has antibacterial activity (By similarity).

    • Tissue specificity

    • Expressed by the skin dorsal glands.

Literature Information

  • ·Literature 1

    • Title

    • New antibiotic uperin peptides from the dorsal glands of the australian toadlet Uperoleia mjobergii.

    • Reference

    • Aust. J. Chem. 1996;49:1325-1331.

    • Author

    • Bradford A.M, Bowie J.H, Tyler M.J, Wallace J.C.