General Information
-
DRAMP ID
- DRAMP01148
-
Peptide Name
- Uperin-3.2 (toads, amphibians, animals)
-
Source
- Uperoleia inundata (Floodplain toadlet)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- GVLDAFRKIATVVKNLV
-
Sequence Length
- 17
-
UniProt Entry
- P82033
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01148.
Physicochemical Information
-
Formula
- C85H147N23O22
Absent Amino Acids
- CEHMPQSWY
Common Amino Acids
- V
Mass
- 1843.24
PI
- 9.99
Basic Residues
- 3
Acidic Residues
- 1
Hydrophobic Residues
- 10
Net Charge
- +2
-
Boman Index
- -5.49
Hydrophobicity
- 0.877
Aliphatic Index
- 148.82
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP01148
Comments Information
Function
- Has antibacterial activity (By similarity).
Tissue specificity
- Expressed by the skin dorsal glands.
Literature Information
- ·Literature 1
-
Title
- Novel uperin peptides from the dorsal glands of the australian floodplain toadlet Uperoleia inundata.
-
Pubmed ID
- PubMed ID is not available
-
Reference
- Aust. J. Chem. 1996; 49:475-484.
-
Author
- Bradford AM, Raftery MJ, Bowie JH, Tyler MJ, Wallace JC, Adams GW, Severini C.