General Information
-
DRAMP ID
- DRAMP01149
-
Peptide Name
- Uperin-3.3 (toads, amphibians, animals)
-
Source
- Uperoleia inundata (Floodplain toadlet)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- GVLDAFKKIATVVKNLV
-
Sequence Length
- 17
-
UniProt Entry
- P82034
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01149.
Physicochemical Information
-
Formula
- C85H147N21O22
Absent Amino Acids
- CEHMPQRSWY
Common Amino Acids
- V
Mass
- 1815.23
PI
- 9.7
Basic Residues
- 3
Acidic Residues
- 1
Hydrophobic Residues
- 10
Net Charge
- +2
-
Boman Index
- 3.88
Hydrophobicity
- 0.912
Aliphatic Index
- 148.82
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP01149
Comments Information
Function
- Has antibacterial activity (By similarity).
Tissue specificity
- Expressed by the skin dorsal glands.
Literature Information
- ·Literature 1
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Title
- Novel uperin peptides from the dorsal glands of the australian floodplain toadlet Uperoleia inundata.
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Pubmed ID
- PubMed ID is not available
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Reference
- Aust. J. Chem. 1996; 49:475-484.
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Author
- Bradford AM, Raftery MJ, Bowie JH, Tyler MJ, Wallace JC, Adams GW, Severini C.