• DRAMP ID

    • DRAMP01157
    • Peptide Name

    • Uperin-4.1 (toads, amphibians, animals)
    • Source

    • Uperoleia inundata (Floodplain toadlet)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GVGSFIHKVVSAIKNVA
    • Sequence Length

    • 17
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacterium: Leuconostoc mesenteroides.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01157 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01157.
    • Formula

    • C79H132N22O21
    • Absent Amino Acids

    • CDELMPQRTWY
    • Common Amino Acids

    • V
    • Mass

    • 1726.05
    • PI

    • 10
    • Basic Residues

    • 3
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Net Charge

    • +3
    • Boman Index

    • 5.28
    • Hydrophobicity

    • 0.9
    • Aliphatic Index

    • 125.88
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP01157

    • Function

    • Shows a medium antibacterial activity against L. mesenteriodes.
    • PTM

    • Alanine amide at position 17.
  • ·Literature 1
    • Title

    • Novel uperin peptides from the dorsal glands of the australian floodplain toadlet Uperoleia inundata.
    • Reference

    • Aust. J. Chem. 1996; 49:475-484.
    • Author

    • Bradford AM, Raftery MJ, Bowie JH, Tyler MJ, Wallace JC, Adams GW, Severini C.