• DRAMP ID

    • DRAMP01172
    • Peptide Name

    • Ocellatin-2 (Frogs, amphibians, animals)
    • Source

    • Leptodactylus ocellatus (Argus frog) (Leptodactylus macrosternum)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GVLDIFKDAAKQILAHAAEKQI
    • Sequence Length

    • 22
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-
    • Target Organism

      • [Swiss_Prot Entry P83866]Gram-negative bacterium: Escherichia coli
    • Hemolytic Activity

      • [Ref:15648972]Show hemolytic activity against human red blood cells
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01172 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01172.
    • Formula

    • C108H179N29O31
    • Absent Amino Acids

    • CMNPRSTWY
    • Common Amino Acids

    • A
    • Mass

    • 2379.78
    • PI

    • 6.75
    • Basic Residues

    • 4
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +1
    • Boman Index

    • -15.03
    • Hydrophobicity

    • 0.196
    • Aliphatic Index

    • 124.55
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 1

DRAMP01172

DRAMP01172 chydropathy plot
    • Function

    • Has hemolytic activity against human erythrocytes and antibacterial activity against the Gram-negative bacterium E. coli.
    • Tissue specificity

    • Expressed by the skin dorsal glands.
  • ·Literature 1
    • Title

    • Ocellatins: new antimicrobial peptides from the skin secretion of the South American frog Leptodactylus ocellatus (Anura: Leptodactylidae).
    • Reference

    • Protein J. 2004 Nov;23(8):501-508.
    • Author

    • Nascimento AC, Zanotta LC, Kyaw CM, Schwartz EN, Schwartz CA, Sebben A, Sousa MV, Fontes W, Castro MS.