• DRAMP ID

    • DRAMP01177
    • Peptide Name

    • Ocellatin-F1 (Fallaxin; Frogs, amphibians, animals)
    • Source

    • Leptodactylus fallax (Mountain chicken frog)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GVVDILKGAAKDIAGHLASKVMNKL
    • Sequence Length

    • 25
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-
    • Target Organism

      • [Ref.15544856]Gram-negative bacteria: Escherichia coli (MIC=40 µM), Pseudomonas aeruginosa (MIC=80 µM), Enterobacter cloacae (MIC=20 µM), Klebsiella pneumoniae (MIC=80 µM).
    • Hemolytic Activity

      • [Ref:15544856]HC50>200 μM hemolytic activity of fallaxin
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Other Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • PDB ID

    • None
    • DRAMP01177 helical wheel diagram
    • Formula

    • C113H198N32O32S
    • Absent Amino Acids

    • CEFPQRTWY
    • Common Amino Acids

    • AK
    • Mass

    • 2549.07
    • PI

    • 9.53
    • Basic Residues

    • 5
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +3
    • Boman Index

    • -5.21
    • Hydrophobicity

    • 0.432
    • Aliphatic Index

    • 128.8
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP01177

DRAMP01177 chydropathy plot
    • Function

    • Has low hemolytic activity of fallaxin (HC50>200 µM).
  • ·Literature 1
    • Title

    • An antimicrobial peptide from the skin secretions of the mountain chicken frog Leptodactylus fallax (Anura:Leptodactylidae).
    • Reference

    • Regul Pept. 2005 Jan 15;124(1-3):173-178.
    • Author

    • Rollins-Smith LA, King JD, Nielsen PF, Sonnevend A, Conlon JM.