• • DRAMP ID

  • DRAMP01184

• • Peptide Name

  • SPX(1-22)(truncated peptide of Syphaxin; Frogs, amphibians, animals)

• • Source

  • Leptodactylus syphax (Burgundy thin-toed frog)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GVLDILKGAAKDLAGHVATKVI

• • Sequence Length

  • 22

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-positive bacterium: Staphylococcus aureus ATCC 29213 (MIC=14.6 µM);
    • Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=40.5 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP01184_predicted_structure.pdb to download.

DRAMP01184

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Antimicrobial peptide from the skin secretion of the frog Leptodactylus syphax.

• • Pubmed ID

  • 17628627

• • Reference

  • Toxicon. 2007 Sep 15;50(4):572-580.

• • Author

  • Dourado F.S, Leite J.R.S.A, Silva L.P, Melo J.A.T, Bloch C. Jr, Schwartz E.F.