• DRAMP ID

    • DRAMP01188
    • Peptide Name

    • Chensinin-1ZHa (Frogs, amphibians, animals)
    • Source

    • Rana zhenhaiensis (Chinese brown frog)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • LALKSGGWLRLFGLKDKKH
    • Sequence Length

    • 19
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=17 µM);
      • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=35 µM), Pseudomonas aeruginosa ATCC 9027 (MIC=9 µM).
      • Yeast: Candida albicans ATCC 2002 (MIC=35 µM).
    • Hemolytic Activity

      • Not found
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Other Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • PDB ID

    • None
    • DRAMP01188 helical wheel diagram
    • Formula

    • C102H167N29O23
    • Absent Amino Acids

    • CEIMNPQTVY
    • Common Amino Acids

    • L
    • Mass

    • 2167.63
    • PI

    • 10.46
    • Basic Residues

    • 6
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 8
    • Net Charge

    • +5
    • Boman Index

    • -19.36
    • Hydrophobicity

    • -0.321
    • Aliphatic Index

    • 107.89
    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 305.56
    • Polar Residues

    • 4

DRAMP01188

DRAMP01188 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis.
    • Reference

    • Zoolog Sci. 2012 Sep;29(9):553-558.
    • Author

    • Xu B, Che H, Kang L, Zheng S, Mu S, Wan F.