• DRAMP ID

    • DRAMP01194
    • Peptide Name

    • Andersonin-C1 (Frogs, amphibians, animals)
    • Source

    • Odorrana andersonii (Golden crossband frog)
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • TSRCIFYRRKKCS
    • Sequence Length

    • 13
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-, Antimicrobial
    • Target Organism

      • [Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=30 µg/ml);
      • Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>120 µg/ml);
      • Yeast: Candida albicans ATCC 2002 (MIC=30 µg/ml).
    • Hemolytic activity

      • [Ref:22029824]15.2±2.1% hemolytic activity at 50μg/ml against human red blood cells
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01194 helical wheel diagram
    • Formula

    • C70H118N24O18S2
    • Absent Amino Acids

    • ADEGHLMNPQVW
    • Common Amino Acids

    • R
    • Mass

    • 1862.18
    • PI

    • 10.88
    • Basic Residues

    • 5
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 2
    • Boman Index

    • -54.91
    • Hydrophobicity

    • -96.92
    • Aliphatic Index

    • 30
    • Half Life

      • Mammalian:7.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1615
    • Absorbance 280nm

    • 134.58
    • Polar Residues

    • 6

DRAMP01194

    • Function

    • Show hemolytic activity against human red blood cells and obvious insulin-stimulating activity at the concentration of 50 μg/mL.
  • Literature 1
    • Reference

    • J Proteome Res. 2012 Jan 1;11(1):306-319.
    • Author

    • Yang X, Lee WH, Zhang Y.
    • Title

    • Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.