• DRAMP ID

    • DRAMP01195
    • Peptide Name

    • Andersonin-D1 (Frogs, amphibians, animals)
    • Source

    • Odorrana andersonii (Golden crossband frog)
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • FIFPKKNIINSLFGR
    • Sequence Length

    • 15
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-, Antimicrobial
    • Target Organism

      • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>126 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=16 µg/ml);
      • Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=16 µg/ml).
      • Yeast: Candida albicans ATCC 2002 (MIC=16 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01195 helical wheel diagram
    • Formula

    • C87H136N22O19
    • Absent Amino Acids

    • ACDEHMQTVWY
    • Common Amino Acids

    • FI
    • Mass

    • 2044.06
    • PI

    • 11.82
    • Basic Residues

    • 3
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 7
    • Boman Index

    • -13.14
    • Hydrophobicity

    • 24
    • Aliphatic Index

    • 104
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 4

DRAMP01195

    • Function

    • Weakly active against bacteria and fungi. Andersonin-D1 showes obvious insulin-stimulating activity at the concentration of 50 μg/mL.
  • Literature 1
    • Reference

    • J Proteome Res. 2012 Jan 1;11(1):306-319.
    • Author

    • Yang X, Lee WH, Zhang Y.
    • Title

    • Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.