• DRAMP ID

    • DRAMP01199
    • Peptide Name

    • Hejiangin-A1 (Frogs, amphibians, animals)
    • Source

    • Odorrana hejiangensis
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • RFIYMKGFGKPRFGKR
    • Sequence Length

    • 16
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-, Antimicrobial
    • Target Organism

      • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=100 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=25 µg/ml);
      • Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=25 µg/ml).
      • Yeast: Candida albicans ATCC 2002 (MIC=50 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01199 helical wheel diagram
    • Formula

    • C94H146N28O18S
    • Absent Amino Acids

    • ACDEHLNQSTVW
    • Common Amino Acids

    • FGKR
    • Mass

    • 2256.14
    • PI

    • 12.27
    • Basic Residues

    • 6
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 4
    • Boman Index

    • -42.52
    • Hydrophobicity

    • -90.63
    • Aliphatic Index

    • 24.38
    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 1490
    • Absorbance 280nm

    • 99.33
    • Polar Residues

    • 4

DRAMP01199

    • Function

    • Hejiangin-A1 showes killing effects against the tested strains.
  • Literature 1
    • Reference

    • J Proteome Res. 2012 Jan 1;11(1):306-319.
    • Author

    • Yang X, Lee WH, Zhang Y.
    • Title

    • Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.