• DRAMP ID

    • DRAMP01200
    • Peptide Name

    • Hejiangin-F1 (frog, amphibians, animals)
    • Source

    • Odorrana hejiangensis
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • IPWKLPATFRPVERPFSKPFCRKD
    • Sequence Length

    • 24
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-, Antimicrobial
    • Target Organism

      • [Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>100 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=100 µg/ml);
      • Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=100 µg/ml);
      • Yeast: Candida albicans ATCC 2002 (MIC=100 µg/ml).
    • Hemolytic activity

      • [Ref:22029824]Non-hemolytic activity against human red blood cells
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01200 helical wheel diagram
    • Formula

    • C138H211N37O31S
    • Absent Amino Acids

    • GHMNQY
    • Common Amino Acids

    • P
    • Mass

    • 3326.88
    • PI

    • 11.04
    • Basic Residues

    • 6
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 8
    • Boman Index

    • -54.67
    • Hydrophobicity

    • -72.5
    • Aliphatic Index

    • 48.75
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 239.13
    • Polar Residues

    • 3

DRAMP01200

DRAMP01200 chydropathy plot
    • Function

    • Weakly active against bacteria and fungi and has no hemolytic activity under the test conditions.
  • Literature 1
    • Reference

    • J Proteome Res. 2012 Jan 1;11(1):306-319.
    • Author

    • Yang X, Lee WH, Zhang Y.
    • Title

    • Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.