General Information

    • DRAMP ID

    • DRAMP01205

    • Peptide Name

    • Dahlein-1.1 (Frogs, amphibians, animals)

    • Source

    • Litoria dahlii (Dahl's aquatic frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GLFDIIKNIVSTL

    • Sequence Length

    • 13

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01205 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01205.

Physicochemical Information

    • Formula

    • C67H113N15O19

    • Absent Amino Acids

    • ACEHMPQRWY

    • Common Amino Acids

    • I

    • Mass

    • 1432.72

    • PI

    • 5.84

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 7

    • Net Charge

    • 0

    • Boman Index

    • 5.68

    • Hydrophobicity

    • 1.177

    • Aliphatic Index

    • 172.31

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP01205

Comments Information

    • Function

    • Weak wide spectrum antimicrobial activity against Gram-positive bacteria.

    • Tissue specificity

    • Expressed by the skin dorsal glands.

Literature Information

  • ·Literature 1

    • Title

    • Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

    • Reference

    • Rapid Commun Mass Spectrom. 2001;15(18):1726-1734.

    • Author

    • Wegener KL, Brinkworth CS, Bowie JH, Wallace JC, Tyler MJ.