• DRAMP ID

    • DRAMP01227
    • Peptide Name

    • Palustrin-1b (Frogs, amphibians, animals)
    • Source

    • Rana palustris (Pickerel frog)
    • Family

    • N/A
    • Gene

    • N/A
    • Sequence

    • ALFSILRGLKKLGNMGQAFVNCKIYKKC
    • Sequence Length

    • 28
    • Evidence code

    • Protein level
    • Biological Activity

    • Antibacterial, Anti-Gram-, Antimicrobial
    • Target Organism

      • Gram-negative bacterium: Escherichia coli (MIC=8 µM).
    • Hemolytic Activity

      • N/A
    • Cytotoxicity

    • Binding Target

    • N/A
    • Linear/Cyclic/Branched

    • N-terminal modification

    • C-terminal modification

    • Other modifications

    • Stereochemistry

    • Structure

    • N/A
    • Structure Description

    • N/A
    • DRAMP01227 helical wheel diagram
    • Formula

    • C143H239N39O34S3
    • Absent Amino Acids

    • DEHPTW
    • Common Amino Acids

    • K
    • Mass

    • 3626.69
    • PI

    • 10.7
    • Basic Residues

    • 6
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 11
    • Boman Index

    • -14.16
    • Hydrophobicity

    • 23.93
    • Aliphatic Index

    • 101.07
    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1615
    • Absorbance 280nm

    • 59.81
    • Polar Residues

    • 9

DRAMP01227

DRAMP01227 chydropathy plot
    • Tissue specificity

    • Expressed by the skin glands.
  • Literature 1
    • Reference

    • Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.
    • Author

    • Basir YJ, Knoop FC, Dulka J, Conlon JM.
    • Title

    • Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.