• DRAMP ID

    • DRAMP01229
    • Peptide Name

    • Palustrin-1d (Frogs, amphibians, animals)
    • Source

    • Rana palustris (Pickerel frog)
    • Family

    • N/A
    • Gene

    • N/A
    • Sequence

    • ALSILKGLEKLAKMGIALTNCKATKKC
    • Sequence Length

    • 27
    • Evidence code

    • Protein level
    • Biological Activity

    • Antibacterial, Anti-Gram-, Antimicrobial
    • Target Organism

      • Gram-negative bacterium: Escherichia coli (MIC=28 µM).
    • Hemolytic Activity

      • N/A
    • Cytotoxicity

    • Binding Target

    • N/A
    • Linear/Cyclic/Branched

    • N-terminal modification

    • C-terminal modification

    • Other modifications

    • Stereochemistry

    • Structure

    • N/A
    • Structure Description

    • N/A
    • DRAMP01229 helical wheel diagram
    • Formula

    • C125H228N34O34S3
    • Absent Amino Acids

    • DFHPQRVWY
    • Common Amino Acids

    • K
    • Mass

    • 3311.55
    • PI

    • 10.51
    • Basic Residues

    • 6
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 11
    • Boman Index

    • -6.82
    • Hydrophobicity

    • 32.22
    • Aliphatic Index

    • 115.93
    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 4.81
    • Polar Residues

    • 8

DRAMP01229

DRAMP01229 chydropathy plot
    • Tissue specificity

    • Expressed by the skin glands.
  • Literature 1
    • Reference

    • Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.
    • Author

    • Basir YJ, Knoop FC, Dulka J, Conlon JM.
    • Title

    • Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.