General Information
-
DRAMP ID
- DRAMP01230
-
Peptide Name
- Palustrin-2a (Frogs, amphibians, animals)
-
Source
- Rana palustris (Pickerel frog)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- GFLSTVKNLATNVAGTVLDTIRCKVTGGCRP
-
Sequence Length
- 31
-
UniProt Entry
- P84278
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram-
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Target Organism
-
- Gram-negative bacterium: Escherichia coli.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01230.
Physicochemical Information
-
Formula
- C137H235N41O42S2
Absent Amino Acids
- EHMQWY
Common Amino Acids
- T
Mass
- 3192.74
PI
- 9.5
Basic Residues
- 4
Acidic Residues
- 1
Hydrophobic Residues
- 11
Net Charge
- +3
-
Boman Index
- -30.43
Hydrophobicity
- 0.3
Aliphatic Index
- 94.19
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 125
Absorbance 280nm
- 4.17
Polar Residues
- 14
DRAMP01230
Comments Information
Tissue specificity
- Expressed by the skin glands.
Literature Information
- ·Literature 1
-
Title
- Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.
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Pubmed ID
- 11087945
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Reference
- Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.
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Author
- Basir YJ, Knoop FC, Dulka J, Conlon JM.