• DRAMP ID

    • DRAMP01232
    • Peptide Name

    • Palustrin-2ISc (Frogs, amphibians, animals)
    • Source

    • Odorrana ishikawae (Ishikawa's frog)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GFMDTAKNVAKNVAATLLDKLKCKITGGC
    • Sequence Length

    • 29
    • Protein Existence

    • Homology
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-negative bacterium: Escherichia coli (MIC=100 µM);
      • Gram-positive bacteria: Staphylococcus aureus (MIC=25 µM), Bacillus subtilis (MIC=12.5 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Cyclic
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Cyclization (Cys23 and Cys29)
    • Nonterminal Modifications and Unusual Amino Acids

    • Disulfide bond between Cys23 and Cys29.
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01232 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01232.
    • Formula

    • C130H224N36O39S3
    • Absent Amino Acids

    • EHPQRSWY
    • Common Amino Acids

    • K
    • Mass

    • 3011.61
    • PI

    • 9.24
    • Basic Residues

    • 5
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 11
    • Net Charge

    • +3
    • Boman Index

    • -20.47
    • Hydrophobicity

    • 0.152
    • Aliphatic Index

    • 87.59
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 4.46
    • Polar Residues

    • 10

DRAMP01232

DRAMP01232 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Characterization of novel antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae by shotgun cDNA cloning.
    • Reference

    • Biochem Biophys Res Commun. 2011 Sep 9;412(4):673-677.
    • Author

    • Iwakoshi-Ukena E, Soga M, Okada G, Fujii T, Sumida M, Ukena K.