• DRAMP ID

    • DRAMP01254
    • Peptide Name

    • Dybowskin-1CDYa (Frogs, amphibians, animals)
    • Source

    • Rana dybowskii (Dybovsky's frog) (Korean brown frog)
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • IIPLPLGYFAKKT
    • Sequence Length

    • 13
    • Evidence code

    • Protein level
    • Biological Activity

    • Antibacterial, Anti-Gram+, Anti-Gram-, Antimicrobial
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus (MIC=6 µM);
      • Gram-negative bacterium: Escherichia coli (MIC=3 µM).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01254 helical wheel diagram
    • Formula

    • C73H117N15O16
    • Absent Amino Acids

    • CDEHMNQRSVW
    • Common Amino Acids

    • IKLP
    • Mass

    • 1675.05
    • PI

    • 10.25
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 6
    • Boman Index

    • 11.6
    • Hydrophobicity

    • 60
    • Aliphatic Index

    • 127.69
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1490
    • Absorbance 280nm

    • 124.17
    • Polar Residues

    • 3

DRAMP01254

    • Tissue specificity

    • Expressed by the skin glands.
  • Literature 1
    • Reference

    • Comp Biochem Physiol B Biochem Mol Biol. 2009 Oct;154(2):174-178.
    • Author

    • Jin LL, Li Q, Song SS, Feng K, Zhang DB, Wang QY, Chen YH.
    • Title

    • Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii.