• DRAMP ID

    • DRAMP01308
    • Peptide Name

    • Phylloseptin-8 (PS-8; Frogs, amphibians, animals)
    • Source

    • Phyllomedusa tomopterna (Tiger-striped leaf frog) (Pithecopus tomopternus)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FLSLIPHAINAVSALAKHF
    • Sequence Length

    • 19
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01308 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01308.
    • Formula

    • C98H153N25O23
    • Absent Amino Acids

    • CDEGMQRTWY
    • Common Amino Acids

    • A
    • Mass

    • 2049.45
    • PI

    • 8.76
    • Basic Residues

    • 3
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +3
    • Boman Index

    • 13.53
    • Hydrophobicity

    • 1.074
    • Aliphatic Index

    • 138.95
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP01308

DRAMP01308 chydropathy plot
    • Function

    • Has antimicrobial activity.
    • Tissue specificity

    • Expressed by the skin glands.
    • PTM

    • C-terminal amidation.
  • ·Literature 1
    • Title

    • Dermaseptins and phylloseptins of Phyllomedusa (Hylidae) secretion.
    • Reference

    • Submitted (FEB-2008) to UniProtKB
    • Author

    • de sa Mandel S.M, Mundim N.C.C.R, Freitas T, Silva L.P, Bloch C. Jr.