• DRAMP ID

    • DRAMP01316
    • Peptide Name

    • Phylloseptin 14 (PS-14; Frogs, amphibians, animals)
    • Source

    • Phyllomedusa azurea (Orange-legged monkey frog) (Phyllomedusa hypochondrialis azurea)
    • Family

    • Not found
    • Gene

    • psn14
    • Sequence

    • FLSLIPAAISAVSALADHF
    • Sequence Length

    • 19
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01316 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01316.
    • Formula

    • C92H143N21O25
    • Absent Amino Acids

    • CEGKMNQRTWY
    • Common Amino Acids

    • A
    • Mass

    • 1943.27
    • PI

    • 5.08
    • Basic Residues

    • 1
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 13
    • Net Charge

    • 0
    • Boman Index

    • 20.07
    • Hydrophobicity

    • 1.5
    • Aliphatic Index

    • 144.21
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP01316

DRAMP01316 chydropathy plot
    • Function

    • Has antimicrobial activity (By similarity).
    • Tissue specificity

    • Expressed by the skin glands.
    • PTM

    • C-terminal amidation.
  • ·Literature 1
    • Title

    • A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea.
    • Reference

    • Peptides. 2007 Jul;28(7):1331-1343.
    • Author

    • Thompson AH, Bjourson AJ, Orr DF, Shaw C, McClean S.