• DRAMP ID

    • DRAMP01338
    • Peptide Name

    • Amolopin-1a (Frogs, amphibians, animals)
    • Source

    • Amolops loloensis (Rufous-spotted torrent frog)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FLPMLAGLAANFLPKLFCKITKKC
    • Sequence Length

    • 24
    • Protein Existence

    • Homology
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus, Bacillus dysenteriae;
      • Gram-negative bacterium: Escherichia coli.
      • Yeast: Candida albicans.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01338 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01338.
    • Formula

    • C127H207N29O27S3
    • Absent Amino Acids

    • DEHQRSVWY
    • Common Amino Acids

    • L
    • Mass

    • 2668.4
    • PI

    • 9.7
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +4
    • Boman Index

    • 18.33
    • Hydrophobicity

    • 0.867
    • Aliphatic Index

    • 110
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 5.43
    • Polar Residues

    • 5

DRAMP01338

DRAMP01338 chydropathy plot
    • Function

    • Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
  • ·Literature 1
    • Title

    • Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis.
    • Reference

    • Peptides. 2006 Dec;27(12):3085-3091.
    • Author

    • Lu Y, Li J, Yu H, Xu X, Liang J, Tian Y, Ma D, Lin G, Huang G, Lai R.