• DRAMP ID

    • DRAMP01339
    • Peptide Name

    • Amolopin-2a (Frogs, amphibians, animals)
    • Source

    • Amolops loloensis (Rufous-spotted torrent frog)
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • FLPIVGKLLSGLSGLL
    • Sequence Length

    • 16
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-, Antimicrobial
    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus (MIC=2.00 µg/ml), Bacillus dysenteriae (MIC=1.50 µg/ml);
      • Gram-negative bacterium: Escherichia coli (MIC=3.00 µg/ml).
      • Candida albicans (MIC=6.50 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01339 helical wheel diagram
    • Formula

    • C79H135N17O19
    • Absent Amino Acids

    • ACDEHMNQRTWY
    • Common Amino Acids

    • L
    • Mass

    • 1894.79
    • PI

    • 9.7
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Boman Index

    • 31.93
    • Hydrophobicity

    • 162.5
    • Aliphatic Index

    • 188.75
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP01339

    • Function

    • Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
  • Literature 1
    • Reference

    • Peptides. 2006 Dec;27(12):3085-3091.
    • Author

    • Lu Y et al Lai R2006
    • Title

    • Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis