General Information

    • DRAMP ID

    • DRAMP01349

    • Peptide Name

    • Tigerinin-RC2 (Frogs, amphibians, animals)

    • Source

    • Fejervarya cancrivora (crab-eating frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RVCMAIPLPLCH

    • Sequence Length

    • 12

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01349 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01349.

Physicochemical Information

    • Formula

    • C59H101N17O13S3

    • Absent Amino Acids

    • DEFGKNQSTWY

    • Common Amino Acids

    • CLP

    • Mass

    • 1352.74

    • PI

    • 8.08

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +2

    • Boman Index

    • 5.94

    • Hydrophobicity

    • 1.175

    • Aliphatic Index

    • 130

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 11.36

    • Polar Residues

    • 2

DRAMP01349

Comments Information

    • Function

    • Amphibian defense peptide.

Literature Information

  • ·Literature 1

    • Title

    • Purification, characterization and cloning of two novel tigerinin-like peptides from skin secretions of Fejervarya cancrivora.

    • Reference

    • Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.

    • Author

    • Lu Y, Song Y, Wang L, Yang H, Zhang K, Lai R.