General Information

    • DRAMP ID

    • DRAMP01385

    • Peptide Name

    • Odorranain-O1 (OdO1; Frogs, amphibians, animals)

    • Source

    • Odorrana grahami (Yunnanfu frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • AVPLIYNRPGIYVTKRPKGK

    • Sequence Length

    • 20

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • [Ref.17272268]Not detectable activity

    • Hemolytic Activity

      • [Ref:17272268]Non-hemolytic activity against rabbit red blood cells

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01385 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01385.

Physicochemical Information

    • Formula

    • C106H176N30O25

    • Absent Amino Acids

    • CDEFHMQSW

    • Common Amino Acids

    • KP

    • Mass

    • 2270.75

    • PI

    • 10.57

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +5

    • Boman Index

    • -29.45

    • Hydrophobicity

    • -0.505

    • Aliphatic Index

    • 92.5

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 156.84

    • Polar Residues

    • 6

DRAMP01385

DRAMP01385 chydropathy plot

Comments Information

    • Function

    • Found no antimicrobial activity against the tested microbes and also has no hemolytic activity against red cell.

Literature Information

  • ·Literature 1

    • Title

    • Anti-infection peptidomics of amphibian skin.

    • Reference

    • Mol Cell Proteomics. 2007 May;6(5):882-894.

    • Author

    • Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J.