• DRAMP ID

    • DRAMP01393
    • Peptide Name

    • Odorranain-W1 (OdW1; Frogs, amphibians, animals)
    • Source

    • Odorrana grahami (Yunnanfu frog) (Rana grahami)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GLFGKSSVWGRKYYVDLAGCAKA
    • Sequence Length

    • 23
    • Protein Existence

    • Transcript level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • [Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=12.60 μg/ml);
      • Gram-positive bacteria: Staphylococcus aureus (MIC=6.30 μg/ml), Bacillus subtilis (MIC=6.30 μg/ml).
      • Yeast: Candida albicans (MIC=3.15 μg/ml).
    • Hemolytic Activity

      • [Ref.17272268] RCH=17.6 ± 2.2% against rabbit red blood cells. RCH, red cell hemolysis.
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Free
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01393 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • Formula

    • C114H174N30O30S
    • Absent Amino Acids

    • EHIMNPQT
    • Common Amino Acids

    • G
    • Mass

    • 2476.88
    • PI

    • 9.52
    • Basic Residues

    • 4
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 9
    • Net Charge

    • +3
    • Boman Index

    • -13.67
    • Hydrophobicity

    • 0.013
    • Aliphatic Index

    • 72.17
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 8480
    • Absorbance 280nm

    • 385.45
    • Polar Residues

    • 9

DRAMP01393

DRAMP01393 chydropathy plot
    • Function

    • Odorranain-W1 has hemolytic activity against rabbit red cell.
  • ·Literature 1
    • Title

    • Anti-infection peptidomics of amphibian skin.
    • Reference

    • Mol Cell Proteomics. 2007 May;6(5):882-894.
    • Author

    • Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J.