General Information
-
DRAMP ID
- DRAMP01488
-
Peptide Name
- Esculentin-1C (Frogs, amphibians, animals)
-
Source
- Unknown
-
Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
-
Gene
- Not found
-
Sequence
- GIFSKLAGKKIKNLISGLKNIGKEVGMDVVRTGIDIAGCKIKGEC
-
Sequence Length
- 45
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Alpha helix
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01488.
Physicochemical Information
-
Formula
- C207H362N58O59S3
Absent Amino Acids
- HPQWY
Common Amino Acids
- GK
Mass
- 4703.68
PI
- 9.63
Basic Residues
- 9
Acidic Residues
- 4
Hydrophobic Residues
- 16
Net Charge
- +5
-
Boman Index
- -32.68
Hydrophobicity
- 0.147
Aliphatic Index
- 110.44
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 125
Absorbance 280nm
- 2.84
Polar Residues
- 15
DRAMP01488
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Structure-activity relationships of antimicrobial peptides from the skin of Rana esculenta inhabiting in Korea.
-
Pubmed ID
- 15232222
-
Reference
- Mol Cells. 2004 Jun 30;17(3):469-476.
-
Author
- Won HS, Kim SS, Jung SJ, Son WS, Lee B, Lee BJ.