General Information

    • DRAMP ID

    • DRAMP01527

    • Peptide Name

    • Nigroain-L antimicrobial peptide (Frogs, amphibians, animals)

    • Source

    • Rana nigrovittata (Black-striped frog) (Hylarana nigrovittata)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FTMKKSLFLILFLGAIPLSMC

    • Sequence Length

    • 21

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01527 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01527.

Physicochemical Information

    • Formula

    • C114H185N23O25S3

    • Absent Amino Acids

    • DEHNQRVWY

    • Common Amino Acids

    • L

    • Mass

    • 2374.04

    • PI

    • 9.31

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +2

    • Boman Index

    • 31.64

    • Hydrophobicity

    • 1.543

    • Aliphatic Index

    • 134.76

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP01527

DRAMP01527 chydropathy plot

Comments Information

    • Function

    • Amphibian defensive peptide.

Literature Information

  • ·Literature 1

    • Title

    • Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovitt.

    • Reference

    • Genomics. 2010 Jan;95(1):66-71.

    • Author

    • Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R.