• • DRAMP ID

  • DRAMP01533

• • Peptide Name

  • Nigroain-B1 (Frogs, amphibians, animals)

• • Source

  • Rana nigrovittata (Black-striped frog)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • CVISAGWNHKIRCKLTGNC

• • Sequence Length

  • 19

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=4.69 µg/ml), S. aureus ATCC43300 (MIC=50.00 µg/ml);
    • Gram-negative bacteria: Pseudomonas aeruginosa PA01 (MIC=25.00 µg/ml), Pseudomonas aeruginosa ATCC27853 (MIC=25.00 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Cyclic

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Cyclization (Cys13 and Cys19)

• • Nonterminal Modifications and Unusual Amino Acids

  • Disulfide bridge between Cys13 and Cys19.

• • Stereochemistry

  • L

• • Structure

  • Bridge

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP01533.

DRAMP01533

• • PTM

  • Contains one disulfide bridge.

• ·Literature 1

• • Title

  • Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata.

• • Pubmed ID

  • 19778602

• • Reference

  • Genomics. 2010 Jan;95(1):66-71.

• • Author

  • Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R.