General Information

    • DRAMP ID

    • DRAMP01581

    • Peptide Name

    • Caerin 1.14 (Frogs, amphibians, animals)

    • Source

    • Litoria caerulea (Green tree frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • SVLGKSVAKHLPHVVPVIAEKT

    • Sequence Length

    • 22

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01581 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01581.

Physicochemical Information

    • Formula

    • C106H181N29O28

    • Absent Amino Acids

    • CDFMNQRWY

    • Common Amino Acids

    • V

    • Mass

    • 2309.78

    • PI

    • 9.7

    • Basic Residues

    • 5

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +4

    • Boman Index

    • -2.63

    • Hydrophobicity

    • 0.418

    • Aliphatic Index

    • 128.18

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP01581

DRAMP01581 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.

    • Reference

    • Eur J Biochem. 2003 May;270(9):2068-2081.

    • Author

    • Vanhoye D, Bruston F, Nicolas P, Amiche M.