General Information

    • DRAMP ID

    • DRAMP01631

    • Peptide Name

    • Dermaseptin-S7 (Frogs, amphibians, animals)

    • Source

    • Phyllomedusa sauvagei (Sauvage's leaf frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GLWKSLLKNVGKAAGKAALNAVTDMVNQ

    • Sequence Length

    • 28

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01631 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01631.

Physicochemical Information

    • Formula

    • C128H217N37O37S

    • Absent Amino Acids

    • CEFHIPRY

    • Common Amino Acids

    • A

    • Mass

    • 2898.42

    • PI

    • 10

    • Basic Residues

    • 4

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +3

    • Boman Index

    • -14

    • Hydrophobicity

    • 0.071

    • Aliphatic Index

    • 104.64

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 203.7

    • Polar Residues

    • 8

DRAMP01631

DRAMP01631 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Identification of three novel Phyllomedusa sauvagei dermaseptins (sVI-sVIII) by cloning from a skin secretion-derived cDNA library.

    • Reference

    • Regul Pept. 2003 Nov 15;116(1-3):139-146.

    • Author

    • Chen T, Tang L, Shaw C.