General Information

    • DRAMP ID

    • DRAMP01706

    • Peptide Name

    • Dermaseptin-like DRP-AC-1 (Frogs, amphibians, animals)

    • Source

    • Agalychnis callidryas (Red-eyed tree frog) (Phyllomedusa callidryas)

    • Family

    • Belongs to the frog skin active peptide family (Dermaseptin subfamily)

    • Gene

    • Not found

    • Sequence

    • GLLSGILNTAGGLLGNLIGSLSNGES

    • Sequence Length

    • 26

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01706 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01706.

Physicochemical Information

    • Formula

    • C104H179N29O37

    • Absent Amino Acids

    • CDFHKMPQRVWY

    • Common Amino Acids

    • GL

    • Mass

    • 2427.74

    • PI

    • 4

    • Basic Residues

    • 0

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 10

    • Net Charge

    • -1

    • Boman Index

    • 9.77

    • Hydrophobicity

    • 0.642

    • Aliphatic Index

    • 138.85

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 15

DRAMP01706

DRAMP01706 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.

    • Reference

    • Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.

    • Author

    • Vanhoye D, Bruston F, Nicolas P, Amiche M.