General Information

    • DRAMP ID

    • DRAMP01709

    • Peptide Name

    • Dermaseptin-1 (DStomo01; Frogs, amphibians, animals)

    • Source

    • Phyllomedusa tomopterna (Tiger-striped leaf frog，Pithecopus tomopternus)

    • Family

    • Belongs to the frog skin active peptide family (Dermaseptin subfamily)

    • Gene

    • Not found

    • Sequence

    • ALWKDLLKNVGIAAGKAVLNKVTDMVNQ

    • Sequence Length

    • 28

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01709 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01709.

Physicochemical Information

    • Formula

    • C135H229N37O38S

    • Absent Amino Acids

    • CEFHPRSY

    • Common Amino Acids

    • AKLV

    • Mass

    • 3010.59

    • PI

    • 9.53

    • Basic Residues

    • 4

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 14

    • Net Charge

    • +2

    • Boman Index

    • -13.11

    • Hydrophobicity

    • 0.236

    • Aliphatic Index

    • 125.36

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 203.7

    • Polar Residues

    • 6

DRAMP01709

DRAMP01709 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Dermaseptins and phylloseptins of Phyllomedusa (Hylidae) secretion.

    • Reference

    • Submitted (APR-2008) to UniProtKB.

    • Author

    • de Sa Mandel S.M, Mundim N.C.C.R, Silva L.P, Prates M.V, Bloch C. Jr.