• DRAMP ID

    • DRAMP01718
    • Peptide Name

    • Dermatoxin-J1 (DRT-J1; Frogs, amphibians, animals)
    • Source

    • Phasmahyla jandaia (Jandaia leaf frog)
    • Family

    • Belongs to the frog skin active peptide family (Dermaseptin subfamily)
    • Gene

    • Not found
    • Sequence

    • SLGGFLKGVGKALAGVGKVVADQFGNLLQAGQ
    • Sequence Length

    • 32
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01718 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01718.
    • Formula

    • C140H231N39O40
    • Absent Amino Acids

    • CEHIMPRTWY
    • Common Amino Acids

    • G
    • Mass

    • 3100.61
    • PI

    • 9.7
    • Basic Residues

    • 3
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 15
    • Net Charge

    • +2
    • Boman Index

    • 9.45
    • Hydrophobicity

    • 0.481
    • Aliphatic Index

    • 109.69
    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 10

DRAMP01718

DRAMP01718 chydropathy plot
    • Function

    • Antimicrobial peptide.
    • Tissue specificity

    • Expressed by the skin glands.
    • PTM

    • C-terminal amidation.
  • ·Literature 1
    • Title

    • Peptidomic dissection of the skin secretion of Phasmahyla jandaia (Bokermann and Sazima, 1978) (Anura, Hylidae, Phyllomedusinae).
    • Reference

    • Toxicon. 2011 Jan;57(1):35-52.
    • Author

    • Rates B, Silva LP, Ireno IC, Leite FS, Borges MH, Bloch C Jr, De Lima ME, Pimenta AM.