• • DRAMP ID

  • DRAMP01721

• • Peptide Name

  • [T5k]temporin-DRa (Frogs, amphibians, animals)

• • Source

  • Rana draytonii

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • HFLGKLVNLAKKIL

• • Sequence Length

  • 14

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial

• • Target Organism

  • • Clinical isolates: Propionibacterium acnes strain ATCC 11828 (MIC=6 µM), P. acnes strain 32548 (MIC=6 µM), P. acnes strain 33257 (MIC=12.5 µM), P. acnes strain 50247 (MIC=3 µM), P. acnes strain 18380 (MIC=12.5 µM), P. acnes strain 15725 (MIC=6 µM), P. acnes strain 29903 (MIC=12.5 µM), P. acnes strain 31766 (MIC=3 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • Mixed (5D-Lys)

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP01721.

DRAMP01721

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Peptides with antimicrobial and anti-inflammatory activities that have therapeutic potential for treatment of acne vulgaris.

• • Pubmed ID

  • 22374306

• • Reference

  • Peptides. 2012 Apr;34(2):275-282.

• • Author

  • Popovic S, Urbán E, Lukic M, Conlon JM.