General Information

    • DRAMP ID

    • DRAMP01747

    • Peptide Name

    • Temporin-1CEe (Frogs, amphibians, animals)

    • Source

    • Rana chensinensis (Chinese brown frog)

    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)

    • Gene

    • Not found

    • Sequence

    • ILPIIGKILSTIF

    • Sequence Length

    • 13

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01747 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01747.

Physicochemical Information

    • Formula

    • C71H122N14O16

    • Absent Amino Acids

    • ACDEHMNQRVWY

    • Common Amino Acids

    • I

    • Mass

    • 1427.83

    • PI

    • 8.75

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +1

    • Boman Index

    • 26.84

    • Hydrophobicity

    • 1.962

    • Aliphatic Index

    • 210

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP01747

Comments Information

    • Temporin-1CEe showed higher antimicrobial activity against Gram-positive bacteria

    • than Gram-negative bacteria.

Literature Information

  • ·Literature 1

    • Title

    • Molecular cloning of novel antimicrobial peptide genes from the skin of the Chinese brown frog, Rana chensinensis.

    • Reference

    • Zoolog Sci. 2011 Feb;28(2):112-117.

    • Author

    • Zhao J, Sun Y, Li Z, Su Q.