General Information
-
DRAMP ID
- DRAMP01754
-
Peptide Name
- Temporin-1CEb (Frogs, amphibians, animals)
-
Source
- Rana chensinensis (Chinese brown frog)
-
Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
-
Gene
- Not found
-
Sequence
- ILPILSLIGGLLGK
-
Sequence Length
- 14
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
-
Target Organism
-
- Gram-positive bacteria: Staphylococcus aureus (MIC=41 µM), Bacillus cereus (MIC=41 µM), Streptococcus lactis (MIC=41 µM);
- Gram-negative bacterium: Escherichia coli (MIC>100 µM).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
- No cytotoxicity information found in the reference(s) presented
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Amidation
-
Nonterminal Modifications and Unusual Amino Acids
- Free
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01754.
Physicochemical Information
-
Formula
- C68H123N15O16
Absent Amino Acids
- ACDEFHMNQRTVWY
Common Amino Acids
- L
Mass
- 1406.82
PI
- 8.75
Basic Residues
- 1
Acidic Residues
- 0
Hydrophobic Residues
- 8
Net Charge
- +1
-
Boman Index
- 33.23
Hydrophobicity
- 1.786
Aliphatic Index
- 222.86
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 4
DRAMP01754
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Molecular cloning of cDNAs encoding antimicrobial peptide precursors from the skin of the Chinese brown frog, Rana chensinensis.
-
Pubmed ID
- 19341344
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Reference
- Zoolog Sci. 2009 Mar;26(3):220-226.
-
Author
- Shang D, Yu F, Li J, Zheng J, Zhang L, Li Y.