General Information
-
DRAMP ID
- DRAMP01755
-
Peptide Name
- Temporin-1TSa (Frogs, amphibians, animals)
-
Source
- Rana tsushimensis (Tsushima brown frog)
-
Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
-
Gene
- Not found
-
Sequence
- FLGALAKIISGIF
-
Sequence Length
- 13
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
-
Target Organism
-
- Gram-positive bacterium: Staphylococcus aureus (MIC=4 µM);
- Gram-negative bacterium: Escherichia coli (MIC>100 µM).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
- No cytotoxicity information found in the reference(s) presented
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Amidation
-
Nonterminal Modifications and Unusual Amino Acids
- Free
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01755.
Physicochemical Information
-
Formula
- C67H108N14O15
Absent Amino Acids
- CDEHMNPQRTVWY
Common Amino Acids
- I
Mass
- 1349.68
PI
- 8.75
Basic Residues
- 1
Acidic Residues
- 0
Hydrophobic Residues
- 9
Net Charge
- +1
-
Boman Index
- 27.11
Hydrophobicity
- 1.908
Aliphatic Index
- 165.38
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP01755
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Antimicrobial peptides from the skin of the Tsushima brown frog Rana tsushimensis.
-
Pubmed ID
- 16413829
-
Reference
- Comp Biochem Physiol C Toxicol Pharmacol. 2006 May;143(1):42-49.
-
Author
- Conlon JM, Al-Ghaferi N, Abraham B, Sonnevend A, Coquet L, Leprince J, Jouenne T, Vaudry H, Iwamuro S.