• DRAMP ID

    • DRAMP01768
    • Peptide Name

    • Temporin-1SKa (Frogs, amphibians, animals)
    • Source

    • Rana sakuraii (stream brown frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • FLPVILPVIGKLLNGIL
    • Sequence Length

    • 17
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-negative bacteria: Escherichia coli (MIC>50 µM);
      • Gram-negative bacteria: Staphylococcus aureus (MIC=25 µM).
      • Fungi: Candida albicans (MIC>50 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Amidation
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01768 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01768.
    • Formula

    • C91H155N19O19
    • Absent Amino Acids

    • ACDEHMQRSTWY
    • Common Amino Acids

    • L
    • Mass

    • 1819.35
    • PI

    • 8.75
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 11
    • Net Charge

    • +1
    • Boman Index

    • 40.11
    • Hydrophobicity

    • 1.9
    • Aliphatic Index

    • 217.65
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP01768

    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii.
    • Reference

    • Peptides. 2007 Mar;28(3):505-514.
    • Author

    • Suzuki H, Iwamuro S, Ohnuma A, Coquet L, Leprince J, Jouenne T, Vaudry H, Taylor CK, Abel PW, Conlon JM.