General Information
-
DRAMP ID
- DRAMP01772
-
Peptide Name
- Temporin-1Ob (Frogs, amphibians, animals)
-
Source
- Rana ornativentris (Japanese mountain brown frog)
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Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
-
Gene
- Not found
-
Sequence
- FLPLIGKILGTILGK
-
Sequence Length
- 15
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
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Target Organism
-
- Gram-positive bacterium: Staphylococcus aureus;
- Gram-negative bacterium: Escherichia coli.
- Yeast: Candida albicans.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01772.
Physicochemical Information
-
Formula
- C78H135N17O17
Absent Amino Acids
- ACDEHMNQRSVWY
Common Amino Acids
- L
Mass
- 1583.03
PI
- 10
Basic Residues
- 2
Acidic Residues
- 0
Hydrophobic Residues
- 8
Net Charge
- +2
-
Boman Index
- 26.57
Hydrophobicity
- 1.347
Aliphatic Index
- 182
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 4
DRAMP01772
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Antimicrobial peptides from the skin of the Japanese mountain brown frog Rana ornativentris: evidence for polymorphism among preprotemporin mRNAs.
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Pubmed ID
- 17147973
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Reference
- Peptides. 2007 Mar;28(3):524-532.
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Author
- Ohnuma A, Conlon JM, Yamaguchi K, Kawasaki H, Coquet L, Leprince J, Jouenne T, Vaudry H, Iwamuro S.