General Information
-
DRAMP ID
- DRAMP01782
-
Peptide Name
- Temporin-LTa (Frogs, amphibians, animals)
-
Source
- Hylarana latouchii (broad-folded frog)
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Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
-
Gene
- Not found
-
Sequence
- FFPLVLGALGSILPKIF
-
Sequence Length
- 17
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
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Target Organism
-
- Gram-positive bacteria: Staphylococcus aureus (MIC=20 µg/ml) and Bacillus subtilis (MIC=10 µg/ml).
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
- No cytotoxicity information found in the reference(s) presented
-
Binding Target
- Cell membrance
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Amidation
-
Nonterminal Modifications and Unusual Amino Acids
- Free
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01782.
Physicochemical Information
-
Formula
- C94H146N18O19
Absent Amino Acids
- CDEHMNQRTWY
Common Amino Acids
- L
Mass
- 1832.3
PI
- 8.75
Basic Residues
- 1
Acidic Residues
- 0
Hydrophobic Residues
- 11
Net Charge
- +1
-
Boman Index
- 37.24
Hydrophobicity
- 1.759
Aliphatic Index
- 160.59
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP01782
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae).
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Pubmed ID
- 19022312
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Reference
- Peptides. 2009 Feb;30(2):273-282.
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Author
- Wang H, Lu Y, Zhang X, Hu Y, Yu H, Liu J, Sun J.