• DRAMP ID

    • DRAMP01784
    • Peptide Name

    • Temporin-LTc (Frogs, amphibians, animals)
    • Source

    • Hylarana latouchii (broad-folded frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Unknow
    • Sequence

    • SLSRFLSFLKIVYPPAF
    • Sequence Length

    • 17
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknow
    • Biological Activity

    • Antibacterial, Antiviral
    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus (MIC=50 µg/ml), Bacillus subtilis (MIC=50 µg/ml);
      • Gram-negative bacterium: Pseudomonas fluorescens (MIC=100 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Traget

    • Unknow
    • Structure

    • Unknow
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP01784 helical wheel diagram
    • Formula

    • C99H149N21O22
    • Absent Amino Acids

    • CDEGHMNQTW
    • Common Amino Acids

    • FLS
    • Mass

    • 2270.95
    • PI

    • 10.45
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Boman Index

    • 3.66
    • Hydrophobicity

    • 88.24
    • Aliphatic Index

    • 114.71
    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1490
    • Absorbance 280nm

    • 93.13
    • Polar Residues

    • 4

DRAMP01784

    • A mutant of the peptide is also HIV inhibitory (Wang G et al. 2010 Antimicrob. Agents Chemother. 54

    • 1343-1346).
  • Literature 1
    • Reference

    • Peptides. 2009 Feb;30(2):273-282.
    • Author

    • Wang H, Lu Y, Zhang X, Hu Y, Yu H, Liu J, Sun J.
    • Title

    • The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae).