• DRAMP ID

    • DRAMP01788
    • Peptide Name

    • Temporin-HN2 (Frogs, amphibians, animals)
    • Source

    • Odorrana hainanensis (Hainan odorous frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • NILNTIINLAKKIL
    • Sequence Length

    • 14
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=4.8 µM), Staphylococcus carnosus KHS (MIC=19 µM), Bacillus licheniformis X39 (MIC=19 µM),Rhodococcus rhodochrous X15 (MIC=2.4 µM);
      • Gram-negative bacterium: Psychrobacter faecalis X29 (MIC=37.5 µM).
      • Fungi: Slime mould 090223 (MIC=9.5 µM) and Candida albicans ATCC2002 (MIC=9.5 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Amidation
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01788 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01788.
    • Formula

    • C73H133N19O19
    • Absent Amino Acids

    • CDEFGHMPQRSVWY
    • Common Amino Acids

    • I
    • Mass

    • 1580.97
    • PI

    • 10
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 8
    • Net Charge

    • +2
    • Boman Index

    • 2.66
    • Hydrophobicity

    • 0.871
    • Aliphatic Index

    • 202.14
    • Half Life

      • Mammalian:1.4 hour
      • Yeast:3 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 4

DRAMP01788

    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis.
    • Reference

    • Peptides. 2012 Jun;35(2):285-290.
    • Author

    • Wang H, Yu Z, Hu Y, Li F, Liu L, Zheng H, Meng H, Yang S, Yang X, Liu J.