• • DRAMP ID

  • DRAMP01799

• • Peptide Name

  • Temporin-1PRa (Temporin 1PRa; Frogs, amphibians, animals)

• • Source

  • Rana pirica (Hokkaido frog)

• • Family

  • Belongs to the frog skin active peptide family (Brevinin subfamily)

• • Gene

  • Not found

• • Sequence

  • ILPILGNLLNGLL

• • Sequence Length

  • 13

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.15003829]Gram-positive bacteria: Staphylococcus aureus (MIC>100 µM);
    • Gram-negative bacteria:Escherichia coli (MIC>100 µM);
    • Fungi:Candida albicans (MIC>100 µM)

• • Hemolytic Activity

  • • [Ref:15003829]HC50>300 μM against washed human erythrocytes

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP01799.

DRAMP01799

• • Function

  • It shows only very weak antimicrobial and hemolytic activity.

• ·Literature 1

• • Title

  • A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica.

• • Pubmed ID

  • 15003829

• • Reference

  • Regul. Pept 2004; 118: 135-141.

• • Author

  • Conlon JM et al Pal T.